Avandia, a compound of rosiglitazone maleate, is an oral antidiabetic agent. Avandia pills increase insulin sensitivity for patients with type 2 diabetes, or non-insulin-dependent diabetes. Avandia also improves glycemic control as it reduces the circulation of insulin levels. If diet, exercise, and a single drug are not enough to control blood sugar levels, Avandia can be used in conjunction with another drug.
Avandia is not to be used for type 1 diabetes (juvenile onset diabetes) or diabetic ketoacidosis. It is questionable whether people with heart failure, fluid retention, or active liver disease should take Avandia at all. Since Avandia became available there have been reports of the development of hepatitis (the inflammation of the liver) due to elevated liver enzymes. Patients taking Avandia should have their liver enzymes monitored regularly.
Additionally, Avandia is in the same class of drugs as Rezulin, a very dangerous drug that has been associated with devastating liver injury including liver failure that can only be cured with transplant. Without immediate transplant, many Rezulin liver failures have resulted in death. Because of this close association with a dangerous drug, users of Avandia should be in close contact with a doctor if they notice any symptoms of liver problems such as nausea, vomiting, stomach pain, fatigue, dark urine, or jaundice. Avandia is also very dangerous for pregnant women and their unborn children.
It is also advised, should you suffer adversely from the use of Avandia, to consult a lawyer. The recent proliferation of dangerous drugs into the marketplace is a disturbing trend, and should a drug threaten your health you should be repaid for damages and the drug should be taken off the market.
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